Where can setup such as Profile, Permission Set, and Permission Set Groups be managed?

The correct response is that the management of setups like Profile, Permission Set, and Permission Set Groups is conducted within a dedicated area of the system designed for user management. This encompasses both the creation and assignment of profiles and permission sets to users, as well as the organization of these permissions into groups for easier management.

Profiles serve as a foundational element in the security model, dictating user access to various system functionalities. Permission Sets provide additional permission layers to users without altering their profiles directly. Permission Set Groups streamline the management of these permission sets by allowing administrators to bundle multiple permission sets together for assignment to users.

In this context, the actual area for managing these settings is found in the User Management Section, which is tailored specifically for handling user permissions and authentication settings. This section simplifies managing the complexities of user access rights across the application.

While Apex Classes, the Settings Menu, and the Permission Management Tool facilitate other important administrative tasks, they do not serve as the primary interface for configuring user profiles and permissions, leading to a more streamlined user management process.